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CLC Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR15469G 100 μl / $495

CLC Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR15469G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CLC antibody (C-term).

Molecular Weight

16453 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytosol. Cytoplasmic granule. Note=Localized in granules from where it may be secreted or transported to other locations in the cell

Host

Rabbit

Species Reactivity

Human

Immunogen

95-124 aa

Target

This CLC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-124 amino acids from the C-terminal region of human CLC.

Isotype

Rabbit Ig

Symbol

LGALS10, LGALS10A

GeneID

UniProt ID

Function

Regulates immune responses through the recognition of cell-surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg).

Summary

Lysophospholipases are enzymes that act on biologicalmembranes to regulate the multifunctional lysophospholipids. Theprotein encoded by this gene is a lysophospholipase expressed ineosinophils and basophils. It hydrolyzes lysophosphatidylcholine toglycerophosphocholine and a free fatty acid. This protein maypossess carbohydrate or IgE-binding activities. It is bothstructurally and functionally related to the galectin family ofbeta-galactoside binding proteins. It may be associated withinflammation and some myeloid leukemias.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Galectin-10, Gal-10, Charcot-Leyden crystal protein, CLC, Eosinophil lysophospholipase, Lysolecithin acylhydrolase, CLC, LGALS10, LGALS10A

Images

Western blot analysis of CLC (arrow) using rabbit polyclonal CLC Antibody (C-term) (Cat. APR15469G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CLC gene.

Specification

Quantity

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