>
Antigen, Antibodies, ELISA, Western Blot >
Primary Antibody >
Polyclonal Antibodies >
PTPRE Antibody (N-term)Brand |
Leading Biology | Catalog Number |
AMM07408G |
Product Type |
Polyclonal Antibodies | Field of Research |
|
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PTPRE antibody (N-term).
|
||
Molecular Weight |
80642 Da
|
||
Cellular Localization |
Antigen Cellular Localization:
Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 3: Cytoplasm.
|
||
Host |
Rabbit
|
||
Species Reactivity |
Human
|
||
Immunogen |
134-163 aa
|
||
Target |
This PTPRE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-163 amino acids from the N-terminal region of human PTPRE.
|
||
Isotype |
Rabbit Ig
|
||
GeneID |
|||
UniProt ID |
|||
Function |
Isoform 1 plays a critical role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function (By similarity).
|
||
Summary |
The protein encoded by this gene is a member of theprotein tyrosine phosphatase (PTP) family. PTPs are known to besignaling molecules that regulate a variety of cellular processesincluding cell growth, differentiation, mitotic cycle, andoncogenic transformation. Two alternatively spliced transcriptvariants of this gene have been reported, one of which encodes areceptor-type PTP that possesses a short extracellular domain, asingle transmembrane region, and two tandem intracytoplasmiccatalytic domains; Another one encodes a PTP that contains adistinct hydrophilic N-terminus, and thus represents anonreceptor-type isoform of this PTP. Studies of the similar genein mice suggested the regulatory roles of this PTP in RAS relatedsignal transduction pathways, cytokines induced SATA signaling, aswell as the activation of voltage-gated K+ channels. [provided byRefSeq].
|
||
Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
||
Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
||
Applications |
WB, IHC-P, E
|
||
Dilution |
WB~~1:1000
IHC-P~~1:10~50
|
||
Synonyms |
Receptor-type tyrosine-protein phosphatase epsilon, Protein-tyrosine phosphatase epsilon, R-PTP-epsilon, PTPRE
|
||
Images |
PTPRE Antibody (N-term) (Cat. AMM07408G) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the PTPRE antibody detected the PTPRE protein (arrow). PTPRE Antibody (N-term) (AMM07408G)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PTPRE Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
||
Specification |
|||
Quantity |
|
Select | Brand | Catalog No. | Product Name | Pack Size | Type | Field of Research | Specification | Quantity | Price(USD) | |
1 | Leading Biology | APR03440G | ITGA11 Antibody (N-term) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask | ||
2 | Leading Biology | APR04537G | CMIP Antibody (C-term) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask | ||
3 | Leading Biology | APR13816G | TRPM5 Antibody | 50 μl | Polyclonal Antibodies |
|
$695.00 | Add Ask | ||
4 | Leading Biology | APR04506G | PCOLCE2 Antibody (Center) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask | ||
5 | Leading Biology | APR12422G | Human H4 Histamine Receptor (extracellular) Antibody | 50 μl | Polyclonal Antibodies |
|
$695.00 | Add Ask | ||
6 | Leading Biology | APR26894N | ASPH Polyclonal Antibody | 100ul | Polyclonal Antibodies | Neuroscience>Calcium Signaling |
|
$495.00 | Add Ask |
Complete this form and click send to ask us a question, request a quote or simply say hello.
You have 0 item in your cart
You have 0 item in your inquiry list