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Polyclonal Antibodies >
QPRT Antibody (C-term)Brand |
Leading Biology | Catalog Number |
AMR09686G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality QPRT antibody (C-term).
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Molecular Weight |
30846 Da
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
206-234 aa
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Target |
This QPRT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-234 amino acids from the C-terminal region of human QPRT.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Involved in the catabolism of quinolinic acid (QA).
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Summary |
This gene encodes a key enzyme in catabolism ofquinolinate, an intermediate in the tryptophan-nicotinamide adeninedinucleotide pathway. Quinolinate acts as a most potent endogenousexitotoxin to neurons. Elevation of quinolinate levels in the brainhas been linked to the pathogenesis of neurodegenerative disorderssuch as epilepsy, Alzheimer's disease, and Huntington's disease.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
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Synonyms |
Nicotinate-nucleotide pyrophosphorylase [carboxylating], Quinolinate phosphoribosyltransferase [decarboxylating], QAPRTase, QPRTase, QPRT
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Images |
QPRT Antibody (C-term) (Cat. AMR09686G) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the QPRT antibody detected the QPRT protein (arrow). QPRT Antibody (C-term) (AMR09686G)immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of QPRT Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
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Specification |
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Quantity |
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