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HCN1 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR12349G 100 μl / $495

HCN1 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR12349G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HCN1 antibody (C-term).

Molecular Weight

98796 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

860-889 aa

Target

This HCN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 860-889 amino acids from the C-terminal region of human HCN1.

Isotype

Rabbit Ig

Symbol

BCNG1

GeneID

UniProt ID

Function

Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). May mediate responses to sour stimuli.

Summary

Hyperpolarization-activated cation channels of the HCNgene family, such as HCN1, contribute to spontaneous rhythmicactivity in both heart and brain.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1, Brain cyclic nucleotide-gated channel 1, BCNG-1, HCN1, BCNG1

Images

HCN1 Antibody (C-term) (Cat. APR12349G) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the HCN1 antibody detected the HCN1 protein (arrow).

HCN1 Antibody (C-term) (APR12349G)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HCN1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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