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CHRD Antibody (C-term)

Catalog # Availability Size / Price Inquiry
AMM05758G 100 μl / $495

CHRD Antibody (C-term)

Brand

Leading Biology

Catalog Number

AMM05758G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CHRD antibody (C-term).

Molecular Weight

102032 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human

Immunogen

926-955 aa

Target

This CHRD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 926-955 amino acids from the C-terminal region of human CHRD.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes (By similarity).

Summary

CHRD is a secreted protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes. This protein may also have roles in organogenesis and during adulthood.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

Chordin, CHRD

Images

Western blot analysis of anti-CHRD Antibody (C-term) (RB14089) in HepG2 cell line lysates (35ug/lane). CHRD(arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with CHRD antibody (C-term) (Cat. AMM05758G), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specification

Quantity

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