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SEC22B Antibody (Center)

Catalog # Availability Size / Price Inquiry
AMM07739G 100 μl / $495

SEC22B Antibody (Center)

Brand

Leading Biology

Catalog Number

AMM07739G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SEC22B antibody (Center).

Molecular Weight

24593 Da

Cellular Localization

Antigen Cellular Localization: Endoplasmic reticulum membrane; Single-pass type IV membrane protein Endoplasmic reticulum-Golgi intermediate compartment membrane. Golgi apparatus, cis-Golgi network membrane. Golgi apparatus, trans-Golgi network membrane. Melanosome Note=Concentrated most in the intermediate compartment/cis-Golgi network and the cis-Golgi cisternae 1 and 2. Greatly reduced in concentration at the trans end of the Golgi apparatus. Identified by mass spectrometry in melanosome fractions from stage I to stage IV

Host

Rabbit

Species Reactivity

Human

Immunogen

75-104 aa

Target

This SEC22B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-104 amino acids from the Central region of human SEC22B.

Isotype

Rabbit Ig

Symbol

SEC22L1

GeneID

UniProt ID

Function

SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.

Summary

The protein encoded by this gene is a member of the SEC22family of vesicle trafficking proteins. It seems to complex withSNARE and it is thought to play a role in the ER-Golgi proteintrafficking. This protein has strong similarity to Mus musculus andCricetulus griseus proteins.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

Vesicle-trafficking protein SEC22b, ER-Golgi SNARE of 24 kDa, ERS-24, ERS24, SEC22 vesicle-trafficking protein homolog B, SEC22 vesicle-trafficking protein-like 1, SEC22B, SEC22L1

Images

SEC22B Antibody (Center) (Cat. AMM07739G) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the SEC22B antibody detected the SEC22B protein (arrow).

SEC22B Antibody (Center) (AMM07739G)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SEC22B Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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