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Polyclonal Antibodies >
PTPLA Antibody (N-term)Brand |
Leading Biology | Catalog Number |
AMR09653G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PTPLA antibody (N-term).
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Molecular Weight |
32388 Da
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Cellular Localization |
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
37-66 aa
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Target |
This PTPLA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the N-terminal region of human PTPLA.
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Isotype |
Rabbit Ig
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Symbol |
HACD1
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GeneID |
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UniProt ID |
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Function |
Responsible for the dehydration step in very long-chain fatty acid (VLCFA) synthesis.
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Summary |
The protein encoded by this gene contains a characteristiccatalytic motif of the protein tyrosine phosphatases (PTPs) family.The PTP motif of this protein has the highly conserved arginineresidue replaced by a proline residue; thus it may represent adistinct class of PTPs. Members of the PTP family are known to besignaling molecules that regulate a variety of cellular processes.This gene was preferentially expressed in both adult and fetalheart. A much lower expression level was detected in skeletal andsmooth muscle tissues, and no expression was observed in othertissues. The tissue specific expression in the developing and adultheart suggests a role in regulating cardiac development anddifferentiation.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
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Synonyms |
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1, 3-hydroxyacyl-CoA dehydratase 1, HACD1, Cementum attachment protein, Protein-tyrosine phosphatase-like member A, PTPLA, HACD1
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Images |
PTPLA Antibody (N-term) (Cat. AMR09653G) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the PTPLA antibody detected the PTPLA protein (arrow). PTPLA Antibody (N-term) (Cat. AMR09653G)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PTPLA Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
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Specification |
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Quantity |
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