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PAICS Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR08919G 100 μl / $495

PAICS Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR08919G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PAICS antibody (N-term).

Molecular Weight

47079 Da

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

95-123 aa

Target

This PAICS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-123 amino acids from the N-terminal region of human PAICS.

Isotype

Rabbit Ig

Symbol

ADE2, AIRC, PAIS

GeneID

UniProt ID

Summary

This gene encodes a bifunctional enzyme containingphosphoribosylaminoimidazole carboxylase activity in its N-terminalregion and phosphoribosylaminoimidazole succinocarboxamidesynthetase in its C-terminal region. It catalyzes steps 6 and 7 ofpurine biosynthesis. The gene is closely linked and divergentlytranscribed with a locus that encodes an enzyme in the samepathway, and transcription of the two genes is coordinatelyregulated. The human genome contains several pseudogenes of thisgene. Multiple transcript variants encoding different isoforms havebeen found for this gene.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:10~50 FC~~1:10~50

Synonyms

Multifunctional protein ADE2, Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase, Phosphoribosylaminoimidazole carboxylase, AIR carboxylase, AIRC, PAICS, ADE2, AIRC, PAIS

Images

PAICS Antibody (N-term) (Cat. APR08919G) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PAICS antibody detected the PAICS protein (arrow).

PAICS Antibody (N-term) (Cat. APR08919G) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the PAICS antibody detected the PAICS protein (arrow).

PAICS Antibody (N-term) (Cat. APR08919G)immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PAICS Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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