> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > TPM4 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
AMM08299G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TPM4 antibody (N-term).
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Molecular Weight |
28522 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm, cytoskeleton.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
26-54 aa
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Target |
This TPM4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-54 amino acids from the N-terminal region of human TPM4.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium.
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Summary |
This gene encodes a member of the tropomyosin family ofactin-binding proteins involved in the contractile system ofstriated and smooth muscles and the cytoskeleton of non-musclecells. Tropomyosins are dimers of coiled-coil proteins thatpolymerize end-to-end along the major groove in most actinfilaments. They provide stability to the filaments and regulateaccess of other actin-binding proteins. In muscle cells, theyregulate muscle contraction by controlling the binding of myosinheads to the actin filament. Multiple transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, FC, E
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Dilution |
WB~~1:1000
FC~~1:10~50
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Synonyms |
Tropomyosin alpha-4 chain, TM30p1, Tropomyosin-4, TPM4
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Images |
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Specification |
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Quantity |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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