> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > CLDN2 Antibody (C-term Y195)Brand |
Leading Biology | Catalog Number |
APR15479G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CLDN2 antibody (C-term Y195).
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Molecular Weight |
24549 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
174-201 aa
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Target |
This CLDN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-201 amino acids from the C-terminal region of human CLDN2.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity.
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Summary |
This gene product belongs to the claudin protein familywhose members have been identified as major integral membraneproteins localized exclusively at tight junctions. Claudins areexpressed in an organ-specific manner and regulate tissue-specificphysiologic properties of tight junctions. This protein isexpressed in the intestine. Alternatively spliced transcriptvariants with different 5' untranslated region have been found forthis gene.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, FC, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
FC~~1:10~50
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Synonyms |
Claudin-2, SP82, CLDN2
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Images |
Western blot analysis of CLDN2 (arrow) using rabbit polyclonal CLDN2 Antibody (Y195) (Cat. APR15479G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CLDN2 gene.
CLDN2 Antibody (C-term Y195) (Cat. APR15479G)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CLDN2 Antibody (C-term Y195) for immunohistochemistry. Clinical relevance has not been evaluated.
CLDN2 Antibody (C-term Y195) (Cat. APR15479G) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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