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COX6B1 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APG02725G 100 μl / $495

COX6B1 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APG02725G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality COX6B1 antibody (C-term).

Molecular Weight

10192 Da

Cellular Localization

Antigen Cellular Localization: Mitochondrion intermembrane space

Host

Rabbit

Species Reactivity

Human

Immunogen

59-86 aa

Target

This COX6B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-86 amino acids from the C-terminal region of human COX6B1.

Isotype

Rabbit Ig

Symbol

COX6B

GeneID

UniProt ID

Function

Connects the two COX monomers into the physiological dimeric form.

Summary

Cytochrome c oxidase (COX), the terminal enzyme of themitochondrial respiratory chain, catalyzes the electron transferfrom reduced cytochrome c to oxygen. It is a heteromeric complexconsisting of 3 catalytic subunits encoded by mitochondrial genesand multiple structural subunits encoded by nuclear genes. Themitochondrially-encoded subunits function in electron transfer, andthe nuclear-encoded subunits may be involved in the regulation andassembly of the complex. This nuclear gene encodes subunit VIb.Mutations in this gene are associated with severe infantileencephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 andCOX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2,respectively.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

Cytochrome c oxidase subunit 6B1, Cytochrome c oxidase subunit VIb isoform 1, COX VIb-1, COX6B1, COX6B

Images

COX6B1 Antibody (C-term) (Cat. APG02725G) western blot analysis in ZR-75-1,A549,NCI-H292 cell line lysates (35ug/lane).This demonstrates the COX6B1 antibody detected the COX6B1 protein (arrow).

COX6B1 Antibody (C-term) (Cat. APG02725G)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of COX6B1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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