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CALU Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR15259G 100 μl / $495

CALU Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR15259G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CALU antibody (C-term).

Molecular Weight

37107 Da

Cellular Localization

Antigen Cellular Localization: Endoplasmic reticulum lumen. Secreted. Melanosome. Sarcoplasmic reticulum lumen Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV

Host

Rabbit

Species Reactivity

Human

Immunogen

217-246 aa

Target

This CALU antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-246 amino acids from the C-terminal region of human CALU.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity (By similarity).

Summary

The product of this gene is a calcium-binding proteinlocalized in the endoplasmic reticulum (ER) and it is involved insuch ER functions as protein folding and sorting. This proteinbelongs to a family of multiple EF-hand proteins (CERC) thatinclude reticulocalbin, ERC-55, and Cab45 and the product of thisgene. Alternatively spliced transcript variants encoding differentisoforms have been identified.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

Calumenin, Crocalbin, IEF SSP 9302, CALU

Images

CALU Antibody (C-term) (Cat. APR15259G) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the CALU antibody detected the CALU protein (arrow).

CALU Antibody (C-term) (Cat. APR15259G)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CALU Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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