> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SUV4-20H1 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
AMM08063G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SUV4-20H1 antibody (C-term).
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Molecular Weight |
99187 Da
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Cellular Localization |
Antigen Cellular Localization:
Nucleus. Chromosome. Note=Associated with pericentric heterochromatin. CBX1 and CBX5 are required for the localization to pericentric heterochromatin (By similarity).
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
4-20 aa
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Target |
This SUV4-20H1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 759-789 amino acids from the C-terminal region of human SUV4-20H1.
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Isotype |
Rabbit Ig
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Symbol |
KMT5B
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GeneID |
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UniProt ID |
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Function |
Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) (By similarity). Plays a role in myogenesis by regulating the expression of target genes, such as EID3.
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Summary |
This gene encodes a protein that contains a SET domain.SET domains appear to be protein-protein interaction domains thatmediate interactions with a family of proteins that displaysimilarity with dual-specificity phosphatases (dsPTPases). Thefunction of this gene has not been determined. Two alternativelyspliced transcript variants have been found for this gene.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, FC, E
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Dilution |
WB~~1:1000
FC~~1:10~50
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Synonyms |
Histone-lysine N-methyltransferase SUV420H1, Lysine N-methyltransferase 5B, Suppressor of variegation 4-20 homolog 1, Su(var)4-20 homolog 1, Suv4-20h1, SUV420H1, KMT5B
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Images |
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Specification |
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Quantity |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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