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MGP Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR14358G 100 μl / $495

MGP Antibody (Center)

Brand

Leading Biology

Catalog Number

APR14358G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MGP antibody (Center).

Molecular Weight

12353 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human

Immunogen

37-66 aa

Target

This MGP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the Central region of human MGP.

Isotype

Rabbit Ig

Symbol

MGLAP

GeneID

UniProt ID

Function

Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation.

Summary

The protein encoded by this gene is secreted and likelyacts as an inhibitor of bone formation. The encoded protein isfound in the organic matrix of bone and cartilage. Defects in thisgene are a cause of Keutel syndrome (KS). Two transcript variantsencoding different isoforms have been found for this gene.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50

Synonyms

Matrix Gla protein, MGP, Cell growth-inhibiting gene 36 protein, MGP, MGLAP

Images

MGP Antibody (Center) (Cat. APR14358G) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the MGP antibody detected the MGP protein (arrow).

MGP Antibody (Center) (Cat. APR14358G)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MGP Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

MGP Antibody (Center) (Cat. APR14358G) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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