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CNGA4 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
AMM05780G 100 μl / $495

CNGA4 Antibody (N-term)

Brand

Leading Biology

Catalog Number

AMM05780G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CNGA4 antibody (N-term).

Molecular Weight

65999 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Multi-pass membrane protein

Host

Rabbit

Species Reactivity

Mouse

Immunogen

131-160 aa

Target

This CNGA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-160 amino acids from the N-terminal region of human CNGA4.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Second messenger, cAMP, causes the opening of cation- selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection (By similarity).

Summary

CNGA4 is a modulatory subunit of vertebrate cyclicnucleotide-gated membrane channels that transduce odorant signals(Munger et al., 2001 [PubMed 11739959]).

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

Cyclic nucleotide-gated cation channel alpha-4, Cyclic nucleotide-gated channel alpha-4, CNG channel alpha-4, CNG-4, CNG4, CNGA4

Images

CNGA4 Antibody (N-term) (Cat. AMM05780G) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the CNGA4 antibody detected the CNGA4 protein (arrow).

CNGA4 Antibody (N-term) (Cat. AMM05780G)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CNGA4 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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