> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SFRP4 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
AMM07762G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SFRP4 antibody (C-term).
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Molecular Weight |
39827 Da
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Cellular Localization |
Antigen Cellular Localization:
Secreted. Note=Cytoplasmic in ovarian tumor cells
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
318-346 aa
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Target |
This SFRP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-346 amino acids from the C-terminal region of human SFRP4.
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Isotype |
Rabbit Ig
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Symbol |
FRPHE
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GeneID |
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UniProt ID |
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Function |
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 may act as a regulator of adult uterine morphology and function. Increases apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling (By similarity). Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake.
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Summary |
Secreted frizzled-related protein 4 (SFRP4) is a member ofthe SFRP family that contains a cysteine-rich domain homologous tothe putative Wnt-binding site of Frizzled proteins. SFRPs act assoluble modulators of Wnt signaling. The expression of SFRP4 inventricular myocardium correlates with apoptosis related geneexpression.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, FC, E
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Dilution |
WB~~1:1000
FC~~1:10~50
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Synonyms |
Secreted frizzled-related protein 4, sFRP-4, Frizzled protein, human endometrium, FrpHE, SFRP4, FRPHE
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Images |
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Specification |
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Quantity |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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