Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > COPE Antibody (C-term)

COPE Antibody (C-term)

APR15553G Product Datasheet Protocol

Catalog #	Availability	Size / Price	Inquiry
APR15553G		100 μl / $495

Bulk Orders Inquiry

3 Images

Contact Information

Leading Biology Inc.

tel:1-661-524(LBI)-0262
Info@leadingbiology.com

Show All Distributors

COPE Antibody (C-term)

Brand	Leading Biology	Catalog Number	APR15553G
Product Type	Polyclonal Antibodies	Field of Research
Product Overview	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality COPE antibody (C-term).
Molecular Weight	34482 Da
Cellular Localization	Antigen Cellular Localization: Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it
Host	Rabbit
Species Reactivity	Human
Immunogen	273-300 aa
Target	This COPE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-300 amino acids from the C-terminal region of human COPE.
Isotype	Rabbit Ig
GeneID	11316
UniProt ID	O14579
Function	The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated with ADP- ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).
Summary	The product of this gene is an epsilon subunit of coatomerprotein complex. Coatomer is a cytosolic protein complex that bindsto dilysine motifs and reversibly associates with Golginon-clathrin-coated vesicles. It is required for budding from Golgimembranes, and is essential for the retrograde Golgi-to-ERtransport of dilysine-tagged proteins. Coatomer complex consists ofat least the alpha, beta, beta', gamma, delta, epsilon and zetasubunits. Alternatively spliced transcript variants encodingdifferent isoforms have been identified.
Form	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage & Stability	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Applications	WB, IHC-P, IF, E
Dilution	WB~~1:1000 IHC-P~~1:10~50 IF~~1:10~50
Synonyms	Coatomer subunit epsilon, Epsilon-coat protein, Epsilon-COP, COPE
Images	All lanes : Anti-COPE Antibody (C-term) at 1:1000 dilution Lane 1: A375 whole cell lysate Lane 2: MCF-7 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 34 kDa Blocking/Dilution buffer: 5% NFDM/TBST. COPE Antibody (C-term) (Cat. APR15553G)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of COPE Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. Confocal immunofluorescent analysis of COPE Antibody (C-term)( APR15553G) with A375 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Specification	Product Datasheet Protocol
Quantity

Add to cart Inquiry

Previous Product: ALDH6A1 Polyclonal Antibody Next Product: p53 Antibody (S15)

Best Sellers

Related Products

Select	Brand	Catalog No.	Product Name	Pack Size	Type	Field of Research	Specification	Quantity	Price(USD)
1	Leading Biology	APR03440G	ITGA11 Antibody (N-term)	100 μl	Polyclonal Antibodies				$495.00	Add Ask
2	Leading Biology	APR04537G	CMIP Antibody (C-term)	100 μl	Polyclonal Antibodies				$495.00	Add Ask
3	Leading Biology	APR12422G	Human H4 Histamine Receptor (extracellular) Antibody	50 μl	Polyclonal Antibodies				$695.00	Add Ask
4	Leading Biology	APR03844G	UBE2W Antibody (C-term)	100 μl	Polyclonal Antibodies				$495.00	Add Ask
5	Leading Biology	APR04349G	HECTD2 Antibody (N-term)	100 μl	Polyclonal Antibodies				$495.00	Add Ask
6	Leading Biology	APR03502G	IGHG1 Antibody (Center)	100 μl	Polyclonal Antibodies				$495.00	Add Ask