> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > CALCA Antibody (Center)Brand |
Leading Biology | Catalog Number |
APR11539G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CALCA antibody (Center).
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Molecular Weight |
13898 Da
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Cellular Localization |
Antigen Cellular Localization:
Secreted.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
56-83 aa
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Target |
This CALCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-83 amino acids from the Central region of human CALCA.
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Isotype |
Rabbit Ig
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Symbol |
CALC1
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GeneID |
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UniProt ID |
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Function |
CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP.
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Summary |
This gene encodes the peptide hormones calcitonin,calcitonin gene-related peptide and katacalcin by tissue-specificalternative RNA splicing of the gene transcripts and cleavage ofinactive precursor proteins. Calcitonin is involved in calciumregulation and acts to regulate phosphorus metabolism. Calcitoningene-related peptide functions as a vasodilator while katacalcin isa calcium-lowering peptide. Multiple transcript variants encodingdifferent isoforms have been found for this gene.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:50~100
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Synonyms |
Calcitonin gene-related peptide 1, Alpha-type CGRP, Calcitonin gene-related peptide I, CGRP-I, CALCA, CALC1
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Images |
CALCA Antibody (Center) (Cat. APR11539G) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CALCA antibody detected the CALCA protein (arrow).
CALCA Antibody (Center) (Cat. APR11539G)immunohistochemistry analysis in formalin fixed and paraffin embedded human thyroid tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CALCA Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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