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MCHR1 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR12512G 100 μl / $495

MCHR1 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR12512G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MCHR1 antibody (C-term).

Molecular Weight

45963 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein.

Host

Rabbit

Species Reactivity

Human

Immunogen

396-422 aa

Target

This MCHR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-422 amino acids from the C-terminal region of human MCHR1.

Isotype

Rabbit Ig

Symbol

GPR24, SLC1

GeneID

UniProt ID

Function

Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis.

Summary

The protein encoded by this gene, a member of the Gprotein-coupled receptor family 1, is an integral plasma membraneprotein which binds melanin-concentrating hormone. The encodedprotein can inhibit cAMP accumulation and stimulate intracellularcalcium flux, and is probably involved in the neuronal regulationof food consumption. Although structurally similar to somatostatinreceptors, this protein does not seem to bind somatostatin.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50

Synonyms

Melanin-concentrating hormone receptor 1, MCH receptor 1, MCH-R1, MCHR-1, G-protein coupled receptor 24, MCH-1R, MCH1R, MCHR, SLC-1, Somatostatin receptor-like protein, MCHR1, GPR24, SLC1

Images

Anti-MCHR1 Antibody (C-term) at 1:1000 dilution + HL-60 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 46 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

MCHR1 antibody (C-term) (Cat. APR12512G) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MCHR1 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

MCHR1 Antibody (C-term) (Cat. APR12512G) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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