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PDE7B Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR12785G 100 μl / $495

PDE7B Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR12785G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PDE7B antibody (C-term).

Molecular Weight

51835 Da

Host

Rabbit

Species Reactivity

Human

Immunogen

421-450 aa

Target

This PDE7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 421-450 amino acids from the C-terminal region of human PDE7B.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain.

Summary

The 3',5'-cyclic nucleotides cAMP and cGMP function assecond messengers in a wide variety of signal transductionpathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs)catalyze the hydrolysis of cAMP and cGMP to the corresponding5'-monophosphates and provide a mechanism to downregulate cAMP andcGMP signaling. This gene encodes a cAMP-specificphosphodiesterase, a member of the cyclic nucleotidephosphodiesterase family.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

cAMP-specific 3', 5'-cyclic phosphodiesterase 7B, PDE7B

Images

PDE7B Antibody (C-term) (Cat. APR12785G) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the PDE7B antibody detected the PDE7B protein (arrow).

Specification

Quantity

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