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GCC2 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR16094G 100 μl / $495

GCC2 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR16094G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GCC2 antibody (C-term).

Molecular Weight

195910 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

1581-1609 aa

Target

This GCC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1581-1609 amino acids from the C-terminal region of human GCC2.

Isotype

Rabbit Ig

Symbol

KIAA0336, RANBP2L4

GeneID

UniProt ID

Function

Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi-associated microtubules through recruitment of CLASP1 and CLASP2.

Summary

The protein encoded by this gene is a peripheral membraneprotein localized to the trans-Golgi network. It is sensitive tobrefeldin A. This encoded protein contains a GRIP domain which isthought to be used in targeting. Alternative splicing results inmultiple transcript variants.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:50~100

Synonyms

GRIP and coiled-coil domain-containing protein 2, 185 kDa Golgi coiled-coil protein, GCC185, CLL-associated antigen KW-11, CTCL tumor antigen se1-1, Ran-binding protein 2-like 4, RanBP2L4, Renal carcinoma antigen NY-REN-53, GCC2, KIAA0336, RANBP2L4

Images

GCC2 Antibody (C-term) (Cat. APR16094G) western blot analysis in mouse stomach tissue lysates (15ug/lane).This demonstrates the GCC2 antibody detected GCC2 protein (arrow).

GCC2 antibody (C-term) (Cat. APR16094G) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GCC2 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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