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TFB2M Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR07195G 100 μl / $495

TFB2M Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR07195G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TFB2M antibody (C-term).

Molecular Weight

45349 Da

Cellular Localization

Antigen Cellular Localization: Mitochondrion.

Host

Rabbit

Species Reactivity

Human

Immunogen

368-396 aa

Target

This TFB2M antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 368-396 amino acids from the C-terminal region of human TFB2M.

Isotype

Rabbit Ig

Symbol

NS5ATP5

GeneID

UniProt ID

Function

S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC-P, WB, E

Dilution

IHC-P~~1:50~100 WB~~1:1000

Synonyms

Dimethyladenosine transferase 2, mitochondrial, 211-, Hepatitis C virus NS5A-transactivated protein 5, HCV NS5A-transactivated protein 5, Mitochondrial 12S rRNA dimethylase 2, Mitochondrial transcription factor B2, h-mtTFB, h-mtTFB2, hTFB2M, mtTFB2, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2, TFB2M, NS5ATP5

Images

TFB2M Antibody (C-term) (Cat. APR07195G) immunohistochemistry analysis in formalin fixed and paraffin embedded human heart carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TFB2M Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

TFB2M Antibody (C-term) (Cat. APR07195G) western blot analysis in K562,WiDr cell line lysates (35ug/lane).This demonstrates the TFB2M antibody detected the TFB2M protein (arrow).

Specification

Quantity

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