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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > CACNA1G Antibody (internal region)

CACNA1G Antibody (internal region)

Catalog # Availability Size / Price Inquiry
APR15218G 0.1 mg / $495

CACNA1G Antibody (internal region)

Brand

Leading Biology

Catalog Number

APR15218G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CACNA1G antibody (internal region).

Molecular Weight

262472 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Multi-pass membrane protein.

Host

Goat

Isotype

IgG

Symbol

KIAA1123

GeneID

UniProt ID

Function

Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1G gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by mibefradil. A particularity of this type of channel is an opening at quite negative potentials and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.

Summary

This antibody is expected to recognize isoform 1 (NP_061496.2), 4 (NP_938199.1), 5 (NP_938194.1), 8 (NP_938198.1), 9 (NP_938192.1), 10 (NP_938200.1) and isoform 15 (NP_938407.1).

Form

0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

E

Synonyms

Voltage-dependent T-type calcium channel subunit alpha-1G, Cav3.1c, NBR13, Voltage-gated calcium channel subunit alpha Cav3.1, CACNA1G, KIAA1123

Images

Specification

Quantity

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