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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > HCG-beta (Pregnancy & Choriocarcinoma Marker) Antibody - With BSA and Azide

HCG-beta (Pregnancy & Choriocarcinoma Marker) Antibody - With BSA and Azide

Catalog # Availability Size / Price Inquiry
APR07392G 50 μg / $395

HCG-beta (Pregnancy & Choriocarcinoma Marker) Antibody - With BSA and Azide

Brand

Leading Biology

Catalog Number

APR07392G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HCG-beta (Pregnancy & Choriocarcinoma Marker) antibody - With BSA and Azide.

Molecular Weight

22kDa

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Mouse

Species Reactivity

Human

Target

Recombinant hCG beta protein

Clone

HCGb/459

Isotype

IgG1, kappa

Symbol

CGB3

GeneID

UniProt ID

Function

Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.

Summary

This MAb reacts with a protein of 22kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the α and β subunits. The α subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.

Form

0.5 ml at 200ug/ml with BSA and azide

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, E

Synonyms

Choriogonadotropin subunit beta, CG-beta, Chorionic gonadotrophin chain beta, CGB, CGB3

Images

Formalin-fixed, paraffin-embedded human placenta stained with hCG beta MAb (HCGb/459). Note specific membrane staining.

Specification

Quantity

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