> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > AMH Antibody (Center)Brand |
Leading Biology | Catalog Number |
APR14921G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality AMH antibody (Center).
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Molecular Weight |
59195 Da
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Cellular Localization |
Antigen Cellular Localization:
Secreted.
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Immunogen |
424-451 aa
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Target |
This AMH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 424-451 amino acids from the Central region of human AMH.
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Isotype |
Rabbit Ig
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Symbol |
MIF
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GeneID |
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UniProt ID |
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Function |
This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin.
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Summary |
Anti mullerian hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140kD disulphide linked precursor that is cleaved to release the mature 30kD homodimer. Originally classified as a foetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, FC, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
FC~~1:10~50
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Synonyms |
Muellerian-inhibiting factor, Anti-Muellerian hormone, AMH, Muellerian-inhibiting substance, MIS, AMH, MIF
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Images |
Western blot analysis of AMH Antibody (Center) (Cat. APR14921G) in 293 cell line lysates (35ug/lane). AMH (arrow) was detected using the purified Pab.
Western blot analysis of AMH Antibody (Center) (Cat. APR14921G) in mouse liver tissue lysates (35ug/lane). AMH (arrow) was detected using the purified Pab.
AMH Antibody (Center) (Cat. APR14921G) IHC analysis in formalin fixed and paraffin embedded prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the AMH Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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