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AMH Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR14921G 100 μl / $545

AMH Antibody (Center)

Brand

Leading Biology

Catalog Number

APR14921G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AMH antibody (Center).

Molecular Weight

59195 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

424-451 aa

Target

This AMH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 424-451 amino acids from the Central region of human AMH.

Isotype

Rabbit Ig

Symbol

MIF

GeneID

UniProt ID

Function

This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin.

Summary

Anti mullerian hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140kD disulphide linked precursor that is cleaved to release the mature 30kD homodimer. Originally classified as a foetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:10~50 FC~~1:10~50

Synonyms

Muellerian-inhibiting factor, Anti-Muellerian hormone, AMH, Muellerian-inhibiting substance, MIS, AMH, MIF

Images

Western blot analysis of AMH Antibody (Center) (Cat. APR14921G) in 293 cell line lysates (35ug/lane). AMH (arrow) was detected using the purified Pab.

Western blot analysis of AMH Antibody (Center) (Cat. APR14921G) in mouse liver tissue lysates (35ug/lane). AMH (arrow) was detected using the purified Pab.

AMH Antibody (Center) (Cat. APR14921G) IHC analysis in formalin fixed and paraffin embedded prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the AMH Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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