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S39A8 Antibody (Center)

Catalog # Availability Size / Price Inquiry
AMM08679G 100 μl / $545

S39A8 Antibody (Center)

Brand

Leading Biology

Catalog Number

AMM08679G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality S39A8 antibody (Center).

Molecular Weight

49631 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Multi-pass membrane protein. Note=Associated with the lysosomal/endosomal compartment following transfection

Host

Rabbit

Species Reactivity

Human

Immunogen

218-246 aa

Target

This S39A8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-246 amino acids from the Central region of human S39A8.

Isotype

Rabbit Ig

Symbol

BIGM103, ZIP8

GeneID

UniProt ID

Function

Acts as a zinc-influx transporter.

Summary

S39A8 encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC, E

Dilution

WB~~1:1000 FC~~1:10~50

Synonyms

Zinc transporter ZIP8, BCG-induced integral membrane protein in monocyte clone 103 protein, LIV-1 subfamily of ZIP zinc transporter 6, LZT-Hs6, Solute carrier family 39 member 8, Zrt- and Irt-like protein 8, ZIP-8, SLC39A8, BIGM103, ZIP8

Images

Western blot analysis of S39A8 Antibody (Center) (Cat. AMM08679G) in CEM cell line lysates (35ug/lane). S39A8 (arrow) was detected using the purified Pab.

S39A8 Antibody (Center) (Cat. AMM08679G) flow cytometric analysis of CEM cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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