> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > CLDN8 Antibody (Center)Brand |
Leading Biology | Catalog Number |
AMM08582G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CLDN8 antibody (Center).
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Molecular Weight |
24845 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. Note=Localizes to tight junctions in all 3 segments of the epididymis, in the caput found in the lateral margins of principal cells, and in the corpus at the interface between basal and principal cells
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
140-166 aa
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Target |
This CLDN8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-166 amino acids from the Central region of human CLDN8.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Plays a major role in tight junction-specific obliteration of the intercellular space.
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Summary |
CLDN8 is components of epithelial cell tight junctions. Tight junctions regulate movement of solutes and ions through the paracellular space and prevent mixing of proteins and lipids in the outer leaflet of the apical and basolateral plasma membrane domains
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, FC, E
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Dilution |
WB~~1:1000
FC~~1:10~50
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Synonyms |
Claudin-8, CLDN8
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Images |
Western blot analysis of CLDN8 Antibody (Center) (Cat. AMM08582G) in 293 cell line lysates (35ug/lane). CLDN8 (arrow) was detected using the purified Pab.
CLDN8 Antibody (Center) (Cat. AMM08582G) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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