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CLDN8 Antibody (Center)

Catalog # Availability Size / Price Inquiry
AMM08582G 100 μl / $545

CLDN8 Antibody (Center)

Brand

Leading Biology

Catalog Number

AMM08582G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CLDN8 antibody (Center).

Molecular Weight

24845 Da

Cellular Localization

Antigen Cellular Localization: Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. Note=Localizes to tight junctions in all 3 segments of the epididymis, in the caput found in the lateral margins of principal cells, and in the corpus at the interface between basal and principal cells

Host

Rabbit

Species Reactivity

Human

Immunogen

140-166 aa

Target

This CLDN8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-166 amino acids from the Central region of human CLDN8.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Plays a major role in tight junction-specific obliteration of the intercellular space.

Summary

CLDN8 is components of epithelial cell tight junctions. Tight junctions regulate movement of solutes and ions through the paracellular space and prevent mixing of proteins and lipids in the outer leaflet of the apical and basolateral plasma membrane domains

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC, E

Dilution

WB~~1:1000 FC~~1:10~50

Synonyms

Claudin-8, CLDN8

Images

Western blot analysis of CLDN8 Antibody (Center) (Cat. AMM08582G) in 293 cell line lysates (35ug/lane). CLDN8 (arrow) was detected using the purified Pab.

CLDN8 Antibody (Center) (Cat. AMM08582G) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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