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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Twinfilin-2 (PTK9L) Antibody (C-term)

Twinfilin-2 (PTK9L) Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR14076G 100 μl / $545

Twinfilin-2 (PTK9L) Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR14076G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Twinfilin-2 (PTK9L) antibody (C-term).

Molecular Weight

39548 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Cell projection, stereocilium. Note=Perinuclear and G-actin-rich cortical actin structure sublocalization

Host

Rabbit

Species Reactivity

Human

Immunogen

320-349 aa

Target

This Twinfilin-2 (PTK9L) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 320-349 amino acids from the C-terminal region of human Twinfilin-2 (PTK9L).

Isotype

Rabbit Ig

Symbol

PTK9L

GeneID

UniProt ID

Function

Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. May play a role in regulating the mature length of the middle and short rows of stereocilia (By similarity).

Summary

The protein encoded by this gene was identified by its interaction with the catalytic domain of protein kinase C-zeta. The encoded protein contains an actin-binding site and an ATP-binding site. It is most closely related to twinfilin (PTK9), a conserved actin monomer-binding protein.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Twinfilin-2, A6-related protein, hA6RP, Protein tyrosine kinase 9-like, Twinfilin-1-like protein, TWF2, PTK9L

Images

The anti-PTK9L Pab (Cat. APR14076G) is used in Western blot to detect PTK9L in HEPG2 tissue lysate.

Specification

Quantity

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