> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > TRAF3IP2 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
AMM08697G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TRAF3IP2 antibody (C-term).
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Molecular Weight |
64666 Da
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
463-492 aa
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Target |
This TRAF3IP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 463-492 amino acids from the C-terminal region of human TRAF3IP2.
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Isotype |
Rabbit Ig
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Symbol |
C6orf2, C6orf4, C6orf5, C6orf6
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GeneID |
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UniProt ID |
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Function |
Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK.
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Summary |
This gene encodes a protein involved in regulatingresponses to cytokines by members of the Rel/NF-kappaBtranscription factor family. These factors play a central role ininnate immunity in response to pathogens, inflammatory signals andstress. This gene product interacts with TRAF proteins (tumornecrosis factor receptor-associated factors) and either I-kappaBkinase or MAP kinase to activate either NF-kappaB or Jun kinase.Several alternative transcripts encoding different isoforms havebeen identified. Another transcript, which does not encode aprotein and is transcribed in the opposite orientation, has beenidentified. Overexpression of this transcript has been shown toreduce expression of at least one of the protein encodingtranscripts, suggesting it has a regulatory role in the expressionof this gene.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Adapter protein CIKS, Connection to IKK and SAPK/JNK, Nuclear factor NF-kappa-B activator 1, ACT1, TRAF3-interacting protein 2, TRAF3IP2, C6orf2, C6orf4, C6orf5, C6orf6
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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