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IDAS Antibody (N-term)

Catalog # Availability Size / Price Inquiry
AMM08633G 100 μl / $545

IDAS Antibody (N-term)

Brand

Leading Biology

Catalog Number

AMM08633G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IDAS antibody (N-term).

Molecular Weight

41720 Da

Cellular Localization

Antigen Cellular Localization: Nucleus. Note=Excluded from the nucleolus.

Host

Rabbit

Species Reactivity

Human

Immunogen

20-46 aa

Target

This IDAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-46 amino acids from the N-terminal region of human IDAS.

Isotype

Rabbit Ig

Symbol

IDAS, MCI, MCIN

GeneID

UniProt ID

Function

Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome-mediated acentriolar pathway (PubMed:25048963). Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1 (PubMed:21543332, PubMed:24064211).

Summary

Transcription regulator required for multiciliate cell differentiation. Acts by promoting transcription of genes required for multiciliate cell formation. Probably acts in a multiprotein complex By similarity. Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Ref.1

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Multicilin, Multiciliate differentiation and DNA synthesis-associated cell cycle protein, Protein Idas, MCIDAS, IDAS, MCI, MCIN

Images

IDAS Antibody (N-term)(Cat. AMM08633G) western blot analysis in human uterus tissue lysate (35ug/lane).This demonstrates the IDAS antibody detected the IDAS protein (arrow).

Specification

Quantity

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