> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > NMNAT2 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR10899G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality NMNAT2 antibody (N-term).
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Molecular Weight |
34439 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Golgi apparatus
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
13-40 aa
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Target |
This NMNAT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-40 amino acids from the N-terminal region of human NMNAT2.
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Isotype |
Rabbit Ig
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Symbol |
C1orf15, KIAA0479
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GeneID |
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UniProt ID |
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Function |
Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate but with a lower efficiency. Cannot use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity prefers NAD(+), NADH and NAAD as substrates and degrades nicotinic acid adenine dinucleotide phosphate (NHD) less effectively. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+).
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Summary |
This gene product belongs to the nicotinamidemononucleotide adenylyltransferase (NMNAT) enzyme family, membersof which catalyze an essential step in NAD (NADP) biosyntheticpathway. Unlike the other human family member, which is localizedto the nucleus, and is ubiquitously expressed; this enzyme iscytoplasmic, and is predominantly expressed in the brain. Twotranscript variants encoding different isoforms have been found forthis gene.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Nicotinamide mononucleotide adenylyltransferase 2, NMN adenylyltransferase 2, Nicotinate-nucleotide adenylyltransferase 2, NaMN adenylyltransferase 2, NMNAT2, C1orf15, KIAA0479
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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