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Primary Antibody >
Polyclonal Antibodies >
EXT1 Antibody (Center)Brand |
Leading Biology | Catalog Number |
AMM08624G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality EXT1 antibody (Center).
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Molecular Weight |
86255 Da
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Cellular Localization |
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Note=The EXT1/EXT2 complex is localized in the Golgi apparatus
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
298-326 aa
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Target |
This EXT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-326 amino acids from the Central region of human EXT1.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor.
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Summary |
This gene encodes an endoplasmic reticulum-resident typeII transmembrane glycosyltransferase involved in the chainelongation step of heparan sulfate biosynthesis. Mutations in thisgene cause the type I form of multiple exostoses. [provided byRefSeq].
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Exostosin-1, Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Multiple exostoses protein 1, Putative tumor suppressor protein EXT1, EXT1
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Images |
EXT1 Antibody (Center) (Cat. AMM08624G) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the EXT1 antibody detected the EXT1 protein (arrow). |
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Specification |
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Quantity |
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