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EXT1 Antibody (Center)

Catalog # Availability Size / Price Inquiry
AMM08624G 100 μl / $545

EXT1 Antibody (Center)

Brand

Leading Biology

Catalog Number

AMM08624G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality EXT1 antibody (Center).

Molecular Weight

86255 Da

Cellular Localization

Antigen Cellular Localization: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Note=The EXT1/EXT2 complex is localized in the Golgi apparatus

Host

Rabbit

Species Reactivity

Human

Immunogen

298-326 aa

Target

This EXT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-326 amino acids from the Central region of human EXT1.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor.

Summary

This gene encodes an endoplasmic reticulum-resident typeII transmembrane glycosyltransferase involved in the chainelongation step of heparan sulfate biosynthesis. Mutations in thisgene cause the type I form of multiple exostoses. [provided byRefSeq].

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Exostosin-1, Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Multiple exostoses protein 1, Putative tumor suppressor protein EXT1, EXT1

Images

EXT1 Antibody (Center) (Cat. AMM08624G) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the EXT1 antibody detected the EXT1 protein (arrow).

Specification

Quantity

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