> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SECISBP2 Antibody (Center)Brand |
Leading Biology | Catalog Number |
APR10917G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SECISBP2 antibody (Center).
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Molecular Weight |
95462 Da
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Cellular Localization |
Antigen Cellular Localization:
Isoform 1: Nucleus.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
501-530 aa
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Target |
This SECISBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 501-530 amino acids from the Central region of human SECISBP2.
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Isotype |
Rabbit Ig
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Symbol |
SBP2
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GeneID |
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UniProt ID |
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Function |
Binds to the SECIS element in the 3'-UTR of some mRNAs encoding selenoproteins. Binding is stimulated by SELB.
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Summary |
The incorporation of selenocysteine into a proteinrequires the concerted action of an mRNA element called a secinsertion sequence (SECIS), a selenocysteine-specific translationelongation factor and a SECIS binding protein. With these elementsin place, a UGA codon can be decoded as selenocysteine. The genedescribed in this record encodes a nuclear protein that functionsas a SECIS binding protein. Mutations in this gene have beenassociated with a reduction in activity of a specific thyroxinedeiodinase, a selenocysteine-containing enzyme, and abnormalthyroid hormone metabolism.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Selenocysteine insertion sequence-binding protein 2, SECIS-binding protein 2, SECISBP2, SBP2
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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