> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > GABRB2 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR14106G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GABRB2 antibody (C-term).
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Molecular Weight |
59150 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
346-374 aa
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Target |
This GABRB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-374 amino acids from the C-terminal region of human GAB_2.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand- gated chloride channel.
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Summary |
The gamma-aminobutyric acid (GABA) A receptor is amultisubunit chloride channel that mediates the fastest inhibitorysynaptic transmission in the central nervous system. This geneencodes GABA A receptor, beta 2 subunit. It is mapped to chromosome5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2subunits of the GABA A receptor. Alternative splicing of this genegenerates 2 transcript variants, differing by a 114 bp insertion.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Gamma-aminobutyric acid receptor subunit beta-2, GABA(A) receptor subunit beta-2, GABRB2
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Images |
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Specification |
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Quantity |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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