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AKAP4 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
AMM08596G 100 μl / $545

AKAP4 Antibody (N-term)

Brand

Leading Biology

Catalog Number

AMM08596G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AKAP4 antibody (N-term).

Molecular Weight

94477 Da

Cellular Localization

Antigen Cellular Localization: Cell projection, cilium, flagellum. Note=Localizes to the principle piece of the sperm flagellum

Host

Rabbit

Species Reactivity

Human

Immunogen

10-36 aa

Target

This AKAP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-36 amino acids from the N-terminal region of human AKAP4.

Isotype

Rabbit Ig

Symbol

AKAP82

GeneID

UniProt ID

Function

Major structural component of sperm fibrous sheath. Plays a role in sperm motility.

Summary

The A-kinase anchor proteins (AKAPs) are a group ofstructurally diverse proteins, which have the common function ofbinding to the regulatory subunit of protein kinase A (PKA) andconfining the holoenzyme to discrete locations within the cell.This gene encodes a member of the AKAP family. The encoded proteinis localized to the sperm flagellum and may be involved in theregulation of sperm motility. Alternative splicing of this generesults in two transcript variants encoding different isoforms.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

A-kinase anchor protein 4, AKAP-4, A-kinase anchor protein 82 kDa, AKAP 82, hAKAP82, Major sperm fibrous sheath protein, HI, Protein kinase A-anchoring protein 4, PRKA4, AKAP4 (HGNC:374), AKAP82

Images

AKAP4 Antibody (N-term) (Cat. AMM08596G) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the AKAP4 antibody detected the AKAP4 protein (arrow).

AKAP4 Antibody (N-term) (AMM08596G)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of AKAP4 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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