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DTX3 Antibody (N-term )

Catalog # Availability Size / Price Inquiry
AMM08620G 100 μl / $545

DTX3 Antibody (N-term )

Brand

Leading Biology

Catalog Number

AMM08620G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DTX3 antibody (N-term ).

Molecular Weight

37988 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm.

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

20-48 aa

Target

This DTX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-48 amino acids from the N-terminal region of human DTX3.

Isotype

Rabbit Ig

Symbol

RNF154

GeneID

UniProt ID

Function

Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context (By similarity). Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

Summary

DTX3 functions as an E3 ubiquitin ligase (Takeyama et al.,2003 [PubMed 12670957]).

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Probable E3 ubiquitin-protein ligase DTX3, 632-, Protein deltex-3, Deltex3, RING finger protein 154, DTX3, RNF154

Images

DTX3 Antibody (N-term ) (Cat. AMM08620G) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the DTX3 antibody detected the DTX3 protein (arrow).

DTX3 Antibody (N-term ) (Cat. AMM08620G) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the DTX3 antibody detected the DTX3 protein (arrow).

Specification

Quantity

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