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WNT16 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
AMM08525G 100 μl / $545

WNT16 Antibody (C-term)

Brand

Leading Biology

Catalog Number

AMM08525G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality WNT16 antibody (C-term).

Molecular Weight

40690 Da

Cellular Localization

Antigen Cellular Localization: Secreted, extracellular space, extracellular matrix

Host

Rabbit

Species Reactivity

Human

Immunogen

236-265 aa

Target

This WNT16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-265 amino acids from the C-terminal region of human WNT16.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity).

Summary

The WNT gene family consists of structurally related geneswhich encode secreted signaling proteins. These proteins have beenimplicated in oncogenesis and in several developmental processes,including regulation of cell fate and patterning duringembryogenesis. This gene is a member of the WNT gene family. Itcontains two transcript variants diverging at the 5' termini. Thesetwo variants are proposed to be the products of separate promotersand not to be splice variants from a single promoter. They aredifferentially expressed in normal tissues, one of which (variant2) is expressed at significant levels only in the pancreas, whereasanother one (variant 1) is expressed more ubiquitously with highestlevels in adult kidney, placenta, brain, heart, and spleen.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

Protein Wnt-16, WNT16

Images

Western blot analysis of lysates from human brain, mouse brain tissue (from left to right), using WNT16 Antibody (C-term)(Cat. AMM08525G). AMM08525G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.

WNT16 Antibody (C-term) (Cat. AMM08525G) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the WNT16 antibody detected the WNT16 protein (arrow).

WNT16 Antibody (C-term) (Cat. AMM08525G)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of WNT16 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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