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HTR4 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR14117G 100 μl / $545

HTR4 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR14117G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HTR4 antibody (N-term).

Molecular Weight

43761 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein. Endosome. Note=Interaction with SNX27 mediates recruitment to early endosomes, while interaction with SLC9A3R1 and EZR might target the protein to specialized subcellular regions, such as microvilli.

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

1-30 aa

Target

This HTR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HTR4.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

Summary

This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

5-hydroxytryptamine receptor 4, 5-HT-4, 5-HT4, Serotonin receptor 4, HTR4

Images

HTR4 Antibody (N-term) (Cat. APR14117G) western blot analysis in MDA-MB453(lane 1) cell line and mouse liver(lane 2) tissue lysates (35ug/lane).This demonstrates the HTR4 antibody detected the HTR4 protein (arrow).

Specification

Quantity

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