> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SLC12A6 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR14251G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SLC12A6 antibody (N-term).
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Molecular Weight |
127617 Da
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Cellular Localization |
Antigen Cellular Localization:
Basolateral cell membrane; Multi-pass membrane protein
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
13-42 aa
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Target |
This SLC12A6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human SLC12A6.
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Isotype |
Rabbit Ig
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Symbol |
KCC3
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GeneID |
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UniProt ID |
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Function |
Mediates electroneutral potassium-chloride cotransport. May be activated by cell swelling. May contribute to cell volume homeostasis in single cells.
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Summary |
This gene is a member of the K-Cl cotransporter (KCC)family. K-Cl cotransporters are integral membrane proteins thatlower intracellular chloride concentrations below theelectrochemical equilibrium potential. The proteins encoded by thisgene are activated by cell swelling induced by hypotonicconditions. Alternate splicing results in multiple transcriptvariants encoding different isoforms. Mutations in this gene areassociated with agenesis of the corpus callosum with peripheralneuropathy.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
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Synonyms |
Solute carrier family 12 member 6, Electroneutral potassium-chloride cotransporter 3, K-Cl cotransporter 3, SLC12A6, KCC3
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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