> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > DUOX2 Antibody (Center)Brand |
Leading Biology | Catalog Number |
APR14103G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DUOX2 antibody (Center).
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Molecular Weight |
175364 Da
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Cellular Localization |
Antigen Cellular Localization:
Apical cell membrane; Multi-pass membrane protein. Note=Localizes to the apical membrane of epithelial cells
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
513-542 aa
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Target |
This DUOX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 513-542 amino acids from the Central region of human DUOX2.
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Isotype |
Rabbit Ig
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Symbol |
LNOX2, THOX2
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GeneID |
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UniProt ID |
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Function |
Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
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Summary |
The protein encoded by this gene is a glycoprotein and amember of the NADPH oxidase family. The synthesis of thyroidhormone is catalyzed by a protein complex located at the apicalmembrane of thyroid follicular cells. This complex contains aniodide transporter, thyroperoxidase, and a peroxide generatingsystem that includes this encoded protein and DUOX1. This proteinis known as dual oxidase because it has both a peroxidase homologydomain and a gp91phox domain.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, FC, E
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Dilution |
WB~~1:1000
FC~~1:10~50
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Synonyms |
Dual oxidase 2, 1111-, Large NOX 2, Long NOX 2, NADH/NADPH thyroid oxidase p138-tox, NADPH oxidase/peroxidase DUOX2, NADPH thyroid oxidase 2, Thyroid oxidase 2, p138 thyroid oxidase, DUOX2, LNOX2, THOX2
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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