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OTOA Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR14234G 100 μl / $545

OTOA Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR14234G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality OTOA antibody (N-term).

Molecular Weight

128533 Da

Cellular Localization

Antigen Cellular Localization: Apical cell membrane; Lipid- anchor, GPI-anchor; Extracellular side. Secreted, extracellular space, extracellular matrix. Note=At the interface between the apical surface of the epithelia and the overlying acellular gel of the tectorial and otoconial membranes.

Host

Rabbit

Species Reactivity

Mouse

Immunogen

92-120 aa

Target

This OTOA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-120 amino acids from the N-terminal region of human OTOA.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

May act as an adhesion molecule.

Summary

The protein encoded by this gene is specifically expressedin the inner ear, and is located at the interface between theapical surface of the inner ear sensory epithelia and theiroverlying acellular gels. It is prposed that this protein isinvolved in the attachment of the inner ear acellular gels to theapical surface of the underlying nonsensory cells. Mutations inthis gene are associated with autosomal recessive deafness type 22(DFNB22). Alternatively spliced transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

Otoancorin, OTOA

Images

OTOA Antibody (N-term) (Cat. APR14234G) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the OTOA antibody detected the OTOA protein (arrow).

OTOA Antibody (N-term) (Cat. APR14234G)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of OTOA Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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