> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > OTOA Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR14234G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality OTOA antibody (N-term).
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Molecular Weight |
128533 Da
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Cellular Localization |
Antigen Cellular Localization:
Apical cell membrane; Lipid- anchor, GPI-anchor; Extracellular side. Secreted, extracellular space, extracellular matrix. Note=At the interface between the apical surface of the epithelia and the overlying acellular gel of the tectorial and otoconial membranes.
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Host |
Rabbit
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Species Reactivity |
Mouse
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Immunogen |
92-120 aa
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Target |
This OTOA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-120 amino acids from the N-terminal region of human OTOA.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
May act as an adhesion molecule.
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Summary |
The protein encoded by this gene is specifically expressedin the inner ear, and is located at the interface between theapical surface of the inner ear sensory epithelia and theiroverlying acellular gels. It is prposed that this protein isinvolved in the attachment of the inner ear acellular gels to theapical surface of the underlying nonsensory cells. Mutations inthis gene are associated with autosomal recessive deafness type 22(DFNB22). Alternatively spliced transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
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Synonyms |
Otoancorin, OTOA
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Images |
OTOA Antibody (N-term) (Cat. APR14234G) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the OTOA antibody detected the OTOA protein (arrow).
OTOA Antibody (N-term) (Cat. APR14234G)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of OTOA Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
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Specification |
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Quantity |
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Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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