> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > ELMO2 Antibody (Center)Brand |
Leading Biology | Catalog Number |
APR10868G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ELMO2 antibody (Center).
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Molecular Weight |
82615 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Cytoplasm, cytosol. Membrane
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
323-350 aa
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Target |
This ELMO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-350 amino acids from the Central region of human ELMO2.
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Isotype |
Rabbit Ig
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Symbol |
CED12A, KIAA1834
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GeneID |
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UniProt ID |
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Function |
Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
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Summary |
The protein encoded by this gene interacts with thededicator of cyto-kinesis 1 protein. Similarity to a C. elegansprotein suggests that this protein may function in phagocytosis ofapoptotic cells and in cell migration. Alternative splicing resultsin multiple transcript variants encoding the same protein.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, FC, E
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Dilution |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
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Synonyms |
Engulfment and cell motility protein 2, Protein ced-12 homolog A, hCed-12A, ELMO2, CED12A, KIAA1834
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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