> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SEC13 Antibody (Center)Brand |
Leading Biology | Catalog Number |
AMM08682G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SEC13 antibody (Center).
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Molecular Weight |
35541 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex. Note=In interphase, localizes at both sides of the NPC
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
72-100 aa
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Target |
This SEC13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-100 amino acids from the Central region of human SEC13.
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Isotype |
Rabbit Ig
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Symbol |
D3S1231E, SEC13L1, SEC13R
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GeneID |
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UniProt ID |
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Function |
Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. As a component of the GATOR2 complex, inhibits GATOR1 complex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway.
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Summary |
The protein encoded by this gene belongs to the SEC13family of WD-repeat proteins. It is a constituent of theendoplasmic reticulum and the nuclear pore complex. It hassimilarity to the yeast SEC13 protein, which is required forvesicle biogenesis from endoplasmic reticulum during the transportof proteins. Multiple alternatively spliced transcript variantshave been found.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, FC, E
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Dilution |
WB~~1:1000
FC~~1:10~50
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Synonyms |
Protein SEC13 homolog, SEC13-like protein 1, SEC13-related protein, SEC13, D3S1231E, SEC13L1, SEC13R
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Images |
SEC13 Antibody (Center) (Cat. AMM08682G) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SEC13 antibody detected the SEC13 protein (arrow).
SEC13 Antibody (Center) (Cat. AMM08682G) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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