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Primary Antibody >
Polyclonal Antibodies >
Trophinin AntibodyBrand |
Leading Biology | Catalog Number |
APR06921G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Trophinin Antibody.
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Molecular Weight |
Predicted: 78, 157 kDa Observed: 94 kDa
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat
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Target |
TRO; Trophinin antibody is human, mouse and rat reactive. Multiple isoforms of Trophinin are known to exist.
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Isotype |
IgG
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Symbol |
KIAA1114, MAGED3
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GeneID |
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UniProt ID |
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Function |
Could be involved with bystin and tastin in a cell adhesion molecule complex that mediates an initial attachment of the blastocyst to uterine epithelial cells at the time of the embryo implantation. Directly responsible for homophilic cell adhesion.
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Summary |
Trophinin, also known as TRO or MAGED3, is an apical cell adhesion molecule that is implicated in the initial attachment during the process of embryo implantation and functions by mediating cell adhesion between trophoblastic and endometrial epithelial cells (1,2). Trophinin is a membrane protein expressed in chorionic villi trophoblasts and in maternal endometrial epithelial cells in an implantation-dependent manner and interacts with Bystin and Tastin, facilitating cell adhesion and embryo implantation (3,4). The induction of Trophinin expression may be a useful method for improving implantation rates and can be a potential diagnostic factor and biomarker for human cancer (4,5).
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC, E
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Images |
Western blot analysis of Trophinin in rat liver tissue lysate with Trophinin antibody at 1 μg/ml. Immunohistochemistry of TROPHININ in mouse liver tissue with TROPHININ antibody at 10 μg/ml. |
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Specification |
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Quantity |
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$495.00 | Add Ask |
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