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IL-22 Antibody

Catalog # Availability Size / Price Inquiry
APR06857G 0.1 mg / $695

IL-22 Antibody

Brand

Leading Biology

Catalog Number

APR06857G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IL-22 Antibody.

Molecular Weight

Predicted: 20 kDa Observed: 25 kDa

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

IL22; IL-22 antibody is human, mouse, and rat reactive. Multiple isoforms of IL-22 are known to exist.

Isotype

IgG

Symbol

ILTIF, ZCYTO18

GeneID

UniProt ID

Function

Cytokine that contributes to the inflammatory response in vivo.

Summary

Interleukin-22 (IL-22) is a cytokine important for the modulation of tissue responses during inflammation (1). Unlike the distantly related IL-10, IL-22 does not inhibit the production of proinflammatory cytokines in monocytes in response to LPS, but it has some inhibitory effects on IL-4 production from Th2 T cells. IL-22 is expressed by both the adaptive arm of the immune system such as CD4 T cell subsets including Th17 cells, as well as by innate lymphocytes such as NK and LTi-like cells (2). IL-22 is highly expressed in several chronic inflammatory conditions, and studies suggest that IL-22 plays both inflammatory and protective roles (3).

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IF, ICC, E

Images

Western blot analysis of IL-22 in HeLa cell lysate with IL-22 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.

Immunocytochemistry of IL-22 in HeLa cells with IL-22 antibody at 5 μg/mL.

Immunofluorescence of IL-22 in HeLa cells with IL-22 antibody at 20 μg/mL.

Specification

Quantity

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