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KLK4 Antibody

Catalog # Availability Size / Price Inquiry
APR06832G 0.1 mg / $695

KLK4 Antibody

Brand

Leading Biology

Catalog Number

APR06832G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KLK4 Antibody .

Molecular Weight

Predicted: 28 kDa Observed: 31kDa

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human

Target

KLK4; KLK4 antibody is human specific. At least three isoforms of KLK4 are known to exist.

Isotype

IgG

Symbol

EMSP1, PRSS17, PSTS

GeneID

UniProt ID

Function

Involved in enamel formation.

Summary

Kallikreins (KLKs) belong to the serine protease family of proteolytic enzymes having diverse physiological functions (1). Kallikrein 4 (KLK4), also known as prostase or EMSP1 (enamel matrix serine protease 1), contains one peptidase S1 domain and the expression in prostate is regulated by hormone (1,2). Many kallikreins are implicated in carcinogenesis and have potential as novel cancer and other disease biomarkers (3). KLK4 may have additional roles such as functioning as one of the two major enamel proteases identified that process enamel matrix proteins. Defects in KLK4 are the cause of amelogenesis imperfecta hypomaturation type 2A1 (AI2A1) (4).

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of KLK4 in human kidney tissue lysate with KLK4 antibody at 1 μg/ml.

Immunohistochemistry of KLK4 in human kidney tissue with KLK4 antibody at 5 μg/mL.

Immunofluorescence of KLK4 in human kidney tissue with KLK4 antibody at 20 μg/mL.

Specification

Quantity

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