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PRKCDBP Antibody

Catalog # Availability Size / Price Inquiry
APR06810G 0.1 mg / $695

PRKCDBP Antibody

Brand

Leading Biology

Catalog Number

APR06810G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PRKCDBP Antibody.

Molecular Weight

29 kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm {ECO:0000250|UniProtKB:Q91VJ2}.

Host

Rabbit

Species Reactivity

Human, Mouse

Target

PRKCDBP; It is predicted to not cross-react with other members of the cavin family.

Isotype

IgG

Symbol

SRBC

GeneID

UniProt ID

Function

Plays a role in the regulation of the circadian clock. Modulates the period length and phase of circadian gene expression and also regulates expression and interaction of the core clock components PER1/2 and CRY1/2. Seems to have an immune potentiation function.

Summary

PRKCDBP Antibody: The protein kinase C delta (PKC-δ) binding protein (PRKCDBP), also known as cavin-3, is a member of the cavin family of proteins that are involved in caveolin formation and regulation. PRKCDBP was initially identified in a screen of cultured cell lines for proteins that were strongly induced by serum starvation. Studies indicate that PRKCDBP binds not only to PKC-δ but also to caveolin-1 and helps regulate caveolin traffic and function. Similar to other members of the cavin family, the expression of PRKCDBP was found to be down-regulated in various cancer cell lines, suggesting a possible tumor suppressor function of PRKCDBP.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of PRKCDBP in A20 cell lysate with PRKCDBP antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.

Immunohistochemistry of PRKCDBP in human spleen tissue with PRKCDBP antibody at 2.5 μg/ml.

Immunofluorescence of PRKCDBP in human spleen tissue with PRKCDBP antibody at 20 μg/ml.

Specification

Quantity

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