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CCL17 Antibody

Catalog # Availability Size / Price Inquiry
APR06806G 0.1 mg / $695

CCL17 Antibody

Brand

Leading Biology

Catalog Number

APR06806G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CCL17 Antibody.

Molecular Weight

10 kDa

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

CCL17;

Isotype

IgG

Symbol

SCYA17, TARC

GeneID

UniProt ID

Function

Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4.

Summary

CCL17 Antibody: CCL17, also known as TARC, binds to chemokine receptors CCR4 and CCR8 and plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. CCL17 is secreted from monocyte-derived DCs and endothelial cells and is responsible for selective recruitment and migration of activated Th2 lymphocytes. CCL17 is also required for CCR7 and CXCR4-dependent migration of cutaneous dendritic cells under inflammatory conditions.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of CCL17 in rat spleen tissue lysate with CCL17 antibody at (A) 1 and (B) 2 μg/mL

Immunohistochemistry of CCL17 in spleen tissue with CCL17 antibody at 5 μg/ml.

Immunofluorescence of CCL17 in human spleen tissue with CCL17 antibody at 20 μg/ml.

Specification

Quantity

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