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TLX1 Antibody

Catalog # Availability Size / Price Inquiry
APR06822G 0.1 mg / $695

TLX1 Antibody

Brand

Leading Biology

Catalog Number

APR06822G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TLX1 Antibody.

Molecular Weight

Predicted: 36 kDa Observed: 35 kDa

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

TLX1; Multiple isoforms of TLX1 exist due to alternative splicing events. TLX1 antibody is predicted to not cross-react with other TLX proteins.

Isotype

IgG

Symbol

HOX11, TCL3

GeneID

UniProt ID

Function

Controls the genesis of the spleen. Binds to the DNA sequence 5'-GGCGGTAAGTGG-3'.

Summary

TLX1 Antibody: The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX1, also called homeobox11 (HOX11), as it is located outside of the four mammalian Hox clusters, is a DNA-binding nuclear transcription factor. TLX1 encodes a homeobox-domain containing protein and is containing a glycine and proline-rich amino terminus. TLX1 is required for maintenance of the developing spleen and cell survival. TLX1 is highly expressed in T-cell leukemia and lymphoid neoplasias as a result of translocation. TLX1-deficient mice have no spleen.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Images

Western blot analysis of TLX1 in mouse spleen tissue lysate with TLX1 antibody at (A) 1 μg/mL and (B) 2 μg/mL.

Immunohistochemistry of TLX1 in human spleen tissue with TLX1 antibody at 2.5 μg/ml.

Specification

Quantity

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