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TPT1 Antibody

Catalog # Availability Size / Price Inquiry
APR06801G 0.1 mg / $695

TPT1 Antibody

Brand

Leading Biology

Catalog Number

APR06801G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TPT1 Antibody.

Molecular Weight

Predicted: 19 kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

TPT1;

Isotype

IgG

GeneID

UniProt ID

Function

Involved in calcium binding and microtubule stabilization.

Summary

TPT1 Antibody: TPT1 (translationally controlled tumor protein 1) is a 23 kDa member of the TCTP family of calcium binding proteins. TPT1 is localized in the cytoplasm and widely expressed and serves as a transcriptional activator, calcium transporter, histamine inducer and antiapoptotic caspase 3 inhibitor. TPT1 is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. TPT1 plays a pivotal role in allergic diseases and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer’s disease and Down syndrome.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of TPT1 in human brain tissue lysate with TPT1 antibody at (A) 0.5 and (B) 1 μg/mL.

Immunohistochemistry of TPT1 in rat brain tissue with TPT1 antibody at 2.5 μg/ml.

Immunofluorescence of TPT1 in rat brain tissue with TPT1 antibody at 20 μg/ml.

Specification

Quantity

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